Gerasymchuk L, Swami A, Carpenter C F, Samarapungavan D, Batke M, Kanhere R, Robinson-Dunn B, Wilson J D, Szela J
Department of Medicine, Division of Infectious Diseases, William Beaumont Hospital, Royal Oak, Michigan 48073, USA.
Transpl Infect Dis. 2009 Oct;11(5):454-7. doi: 10.1111/j.1399-3062.2009.00415.x. Epub 2009 Jun 23.
We present a case of fulminant leptospirosis that was acquired in the suburban area by a 48-year-old male renal transplant recipient. He developed acute renal and hepatic failure with profound jaundice. Spirochetes were identified on liver biopsy. Weil's disease was suspected, and the diagnosis was further supported by a positive serum Leptospira interrogans icterohaemorrhagiae antibody titer. Unfortunately, he suffered from recurrent lower gastrointestinal bleeding, had a prolonged hospital course, and eventually succumbed to overwhelming sepsis. This case is the third report to our knowledge of leptospirosis in a renal transplant recipient in the English literature.
我们报告一例48岁男性肾移植受者在郊区感染的暴发性钩端螺旋体病。他出现急性肾衰和肝衰，并伴有严重黄疸。肝活检发现了螺旋体。怀疑为韦尔氏病，血清黄疸出血型问号钩端螺旋体抗体滴度呈阳性进一步支持了该诊断。不幸的是，他反复出现下消化道出血，住院时间延长，最终死于严重败血症。据我们所知，该病例是英文文献中关于肾移植受者钩端螺旋体病的第三例报告。
