Sen Tiyas, Udwadia Zarir F
Department of Pulmonary Medicine, P. D. Hinduja National Hospital and Medical Research Centre, Mumbai, India.
Indian J Chest Dis Allied Sci. 2010 Oct-Dec;52(4):207-11.
There has been a recent surge in the recognition of interstitial lung disease (ILD) in India.
We conducted a retrospective study based on the available medical records of 274 patients with biopsy proven ILD seen during the period 1994-2001 at our tertiary care referral hospital.
Idiopathic pulmonary fibrosis (43%), sarcoidosis (22%), ILDs secondary to collagen vascular disease (19%) and extrinsic allergic alveolitis, among others, were the most common aetiological causes of ILD. The diagnostic yield from transbronchial lung biopsy (TBLB) was high (96%).
Interstitial lung diseases (ILDs) appear to be under-reported from India. Lack of recognition and inadequate availability of diagnostic facilities, like high resolution computed tomography (HRCT) of the chest may be some of the reasons for this. The diagnostic yield from TBLB in our study was high at 96 percent. The TBLB may be used as the initial, cost-effective and safe tool for confirmation of aetiological diagnosis in most patients with diffuse parenchymal lung diseases.
近期，印度对间质性肺疾病（ILD）的认识有了显著提高。
我们基于1994年至2001年期间在我们的三级医疗转诊医院就诊的274例经活检证实为ILD患者的现有病历进行了一项回顾性研究。
特发性肺纤维化（43%）、结节病（22%）、继发于胶原血管疾病的ILD（19%）以及外源性过敏性肺泡炎等是ILD最常见的病因。经支气管肺活检（TBLB）的诊断阳性率很高（96%）。
印度的间质性肺疾病（ILD）似乎报告不足。缺乏认识以及诊断设备（如胸部高分辨率计算机断层扫描（HRCT））供应不足可能是部分原因。在我们的研究中，TBLB的诊断阳性率高达96%。TBLB可作为大多数弥漫性实质性肺疾病患者病因诊断的初始、经济有效且安全的工具。
