[用于检测口腔鳞状细胞癌的甲苯胺蓝染色]
[Toluidine blue staining for detection of oral squamous carcinoma].
作者信息
Wiersma A C, van der Waal I
机构信息
Vrije Universiteit, Amsterdam.
出版信息
Ned Tijdschr Tandheelkd. 1990 Oct;97(10):431-2.
PMID:2130265
Abstract
A pilot-study is presented to evaluate the use of Toluidine blue as a screening agent of premalignant and malignant oral lesions. Test results in 20 patients showed that Toluidine blue is effective in staining malignant lesions and not so in premalignant ones. The staining technique appears to be a worthwhile and simple diagnostic aid to support clinical evidence of malignancy. A biopsy remains mandatory in reaching the final diagnosis.
摘要
本文呈现了一项初步研究，以评估甲苯胺蓝作为口腔癌前病变和恶性病变筛查剂的用途。对20名患者的测试结果表明，甲苯胺蓝对恶性病变染色有效，而对癌前病变效果不佳。这种染色技术似乎是一种有价值且简单的诊断辅助手段，可支持恶性肿瘤的临床证据。最终诊断仍必须依靠活检。
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