Tamás P, Gresele P, Polidori D, Nenci G G
Department of Obstetrics and Gynaecology, University Medical School, Pécs, Hungary.
Acta Med Hung. 1990;47(3-4):201-7.
Red blood cell filterability as an appropriate method for evaluating red blood cell deformability was studied with different suspending media of erythrocytes. Comparison of autologous plasma and buffer suspensions of healthy subjects' erythrocytes showed no significant difference in filterability. Albumin alone resulted in a dose-dependent increase, while fibrinogen caused a decrease in red cell filterability. In the presence of fibrinogen, albumin showed controversial effects. The results suggest that measurements of red blood cells in their original surroundings give more accurate information about the microcirculation because plasma components may have a crucial influence on erythrocyte deformability.
采用不同的红细胞悬浮介质，研究了红细胞过滤性作为评估红细胞变形性的一种合适方法。对健康受试者红细胞的自体血浆和缓冲液悬浮液进行比较，结果显示过滤性无显著差异。单独使用白蛋白会导致剂量依赖性增加，而纤维蛋白原会使红细胞过滤性降低。在存在纤维蛋白原的情况下，白蛋白显示出有争议的作用。结果表明，在红细胞原始环境中进行测量能提供关于微循环的更准确信息，因为血浆成分可能对红细胞变形性有至关重要的影响。
