癫痫发生的神经影像学生物标志物。
Neuroimaging biomarkers of epileptogenesis.
机构信息
Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
出版信息
Neurosci Lett. 2011 Jun 27;497(3):194-204. doi: 10.1016/j.neulet.2011.01.076. Epub 2011 Feb 16.
Abstract
Much progress has been made in the field studying the process of epileptogenesis via neuroimaging techniques. Conventional imaging methods include magnetic resonance imaging with morphometric analysis, magnetic resonance spectroscopy and positron emission tomography. Newer network-based methods such as diffusion tensor imaging and functional magnetic resonance imaging with resting functional connectivity are being developed and applied to clinical use. This review provides a brief summary of the major human and animal studies in both partial and generalized epilepsies that demonstrate the potential of these imaging modalities to serve as biomarkers of epileptogenesis.
摘要
在使用神经影像学技术研究癫痫发生过程的领域取得了很大进展。传统的成像方法包括形态计量学磁共振成像、磁共振波谱和正电子发射断层扫描。较新的基于网络的方法，如弥散张量成像和静息功能磁共振成像连接，正在被开发并应用于临床。这篇综述简要总结了部分和全面性癫痫的主要人体和动物研究，这些研究表明这些成像方式有潜力作为癫痫发生的生物标志物。
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