Bregani Enrico Rino, Maraffi Tommaso, Tien Tu Van
Emergency Medicine Division, Fondazione IRCCS Ca' Granda-Ospedale Policlinico, Milan, Italy.
Trop Doct. 2011 Apr;41(2):123-6. doi: 10.1258/td.2010.100224. Epub 2011 Feb 8.
Snake bites are of major public health importance in Africa as a cause of morbidity and mortality. Echis ocellatus is responsible for the majority of envenomation cases in West Africa. Antivenom immunotherapy is the only specific treatment available for envenomed patients. From January 1997 to December 2001, 325 patients suffering from snake bites were enrolled in a survey undertaken at Goundi Hospital, Chad. We analysed the percentage of envenomed patients, sex distribution, distribution along the year, lethality, hospital stay and recovery clotting time. Two hundred and ninety-eight patients showed signs of envenomation and were treated with antivenom immunotherapy with three different sera in consecutive periods. Young males were more frequently involved. The overall lethality was 8%. Lethality and hospital stay were significantly different in the differently treated patients. Most of the data in our series were similar to those from other sub-Saharan countries but, overall, the percentage of snake bite victims who were admitted to hospital was higher.
在非洲,蛇咬伤作为发病和死亡原因,对公共卫生具有重大影响。鼓腹咝蝰是西非大多数蛇咬中毒病例的罪魁祸首。抗蛇毒血清免疫疗法是蛇咬中毒患者唯一可用的特效治疗方法。1997年1月至2001年12月,在乍得的贡迪医院进行的一项调查中,纳入了325例蛇咬伤患者。我们分析了蛇咬中毒患者的百分比、性别分布、全年分布、致死率、住院时间和凝血恢复时间。298例患者出现蛇咬中毒症状,并在连续几个时期使用三种不同的血清进行抗蛇毒血清免疫治疗。年轻男性更常被咬伤。总体致死率为8%。不同治疗组患者的致死率和住院时间存在显著差异。我们系列中的大多数数据与撒哈拉以南其他国家的数据相似,但总体而言,入院的蛇咬伤受害者百分比更高。