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津巴布韦的蛇咬伤:一项强调抗蛇毒血清需求的临床研究。

Snake bites in Zimbabwe: a clinical study with emphasis on the need for antivenom.

作者信息

Muguti G I, Maramba A, Washaya C T

机构信息

Department of Surgery, Mpilo Central Hospital, Bulawayo, Zimbabwe.

出版信息

Cent Afr J Med. 1994 Apr;40(4):83-8.

PMID:7954715
Abstract

A retrospective analysis of 83 consecutive patients (42 males and 41 females) treated for snake bites at Mpilo Central Hospital between January 1990 and June 1992 is presented. In Zimbabwe poisonous snakes belong to four families; Colubrids (Boomslang), Vipers (Puff Adder), Elapids (Mambas and Cobras) and Atractaspids (Bibron Stilleto snake). The Puff Adder is responsible for three quarters of the bites. Forty eight pc (40/83) of the patients were below 20 years of age (range 1 year 10 months to 72 years). Most bites occurred at night (61 pc) in the rainy season (November to April). The majority of snake bites occurred on the lower limb, 64 pc (53/83), with most of the remainder occurring on the upper limb, 34 pc (28/83). The most common clinical features were; pain (95 pc), swelling (87 pc), tachycardia (20 pc), fever (13 pc) and vomiting (8 pc). This study, carried out at a time when there was no antivenom in stock at Mpilo Hospital, shows a considerable mortality (5 pc, 4/83) and morbidity (37 pc, 31/83) rate from poisonous snake bites in Zimbabwe. These observations highlight the need to maintain adequate stocks of antivenom in the major hospitals in Zimbabwe.

摘要

本文对1990年1月至1992年6月期间在姆皮洛中心医院接受治疗的83例连续蛇咬伤患者(42例男性和41例女性)进行了回顾性分析。在津巴布韦,毒蛇分属四个科;游蛇科(树眼镜蛇)、蝰蛇科(鼓腹咝蝰)、眼镜蛇科(曼巴蛇和眼镜蛇)和穴蝰科(比氏穴蝰)。鼓腹咝蝰导致了四分之三的咬伤事件。48%(40/83)的患者年龄在20岁以下(年龄范围为1岁10个月至72岁)。大多数咬伤事件发生在雨季(11月至4月)的夜间(61%)。大多数蛇咬伤发生在下肢,占64%(53/83),其余大部分发生在上肢,占34%(28/83)。最常见的临床特征为:疼痛(95%)、肿胀(87%)、心动过速(20%)、发热(13%)和呕吐(8%)。这项研究是在姆皮洛医院没有库存抗蛇毒血清的时候进行的,结果显示津巴布韦毒蛇咬伤导致的死亡率相当高(5%,4/83),发病率也很高(37%,31/83)。这些观察结果凸显了在津巴布韦各大医院维持充足抗蛇毒血清库存的必要性。

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