Szpirglas H, Goudot P, Thomas A, Guilbert F, Vaillant J M, Touboul E, Nizri D
Service de stomatologie et chirurgie maxillo-faciale, C.H.U. Pitié-Salpêtrière, Paris.
Rev Stomatol Chir Maxillofac. 1990;91 Suppl 1:26-8.
64 patients with extra-nodal maxillo-facial NHL were seen between 1969 and 1989. These rare tumours (1 to 4% of stomatological tumours) tended to occur more often in men (60% of cases) between the ages of 40 and 70. Bony involvement was common (maxillary and mandibular involvement), though more rarely the salivary glands or mucosa were involved, presenting as a swelling with lysis of underlying bone. Highly malignant varieties (85% of cases) were most commonly encountered. The treatment remains medical, involving chemotherapy (C.H.O.P. or high dose methotrexate) and gives an actuarial survival rate of 50% at 3 years.
1969年至1989年间,共诊治了64例结外颌面部非霍奇金淋巴瘤患者。这些罕见肿瘤(占口腔肿瘤的1%至4%)在40至70岁男性中更为常见(占病例的60%)。骨受累很常见(上颌骨和下颌骨受累),不过唾液腺或黏膜受累较少见,表现为伴有下方骨质溶解的肿块。高恶性类型最为常见(占病例的85%)。治疗仍以药物治疗为主,包括化疗(CHOP方案或大剂量甲氨蝶呤),3年精算生存率为50%。