Rozsíval V
I. interní klinika FN KUNZ, Hradec Králové.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1990;33(4):359-63.
Propafenone hydrochloride (Rytmonorm, Prolekofen) belongs to the membranous anti-arrhythmical agents of IC group. Simultaneously, it produces a mild beta blocking effect and blocks slow Calcium channels. The mentioned agent is of current use in treating both the supraventricular and ventricular tachyarrhythmias. Literary experience is referred to in management of arrhythmias with propafenone as well as electrophysiologic properties, pharmacokinetics, hemodynamic effect and side-effects.
盐酸普罗帕酮(心律平,Prolekofen)属于IC类膜活性抗心律失常药物。同时,它具有轻度的β受体阻滞作用,并能阻断慢钙通道。该药物目前用于治疗室上性和室性快速性心律失常。文中提及了使用普罗帕酮治疗心律失常的经验以及其电生理特性、药代动力学、血流动力学效应和副作用。