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左主干病变所致急性心肌梗死的治疗。

The treatment of acute myocardial infarction due to the occlusion of the left main coronary disease.

机构信息

Kartal Kosuyolu Heart and Research Hospital Cardiology, Istanbul, Turkey.

出版信息

Cardiol J. 2011;18(1):77-82.

PMID:21305490
Abstract

Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional cardiologists, because it involves the extension of the myocardium complicated by cardiogenic shock and its technical difficulties. Trifurcating coronary artery disease is a complex atherosclerotic process involving the origin of one or more of three side branches arising from a left main coronary vessel or trunk, with or without the involvement of LMCA itself. There is no classification or standardized methodology to treat LMCA disease in elective percutaneous intervention procedures. Furthermore, acute myocardial infarction presenting with left main coronary artery trifurcation lesion seems to be more troublesome, especially in young patients. Few series of PCI on significant lesions of the left main trifurcations have been described. Herein, we describe a patient who successfully underwent PCI and was supported by post intravascular ultrasound sonography and multislice computed angiography (MSCA), and after an uneventful follow-up with MSCA is now on the ninth month.

摘要

急性心肌梗死(AMI)由于左主干冠状动脉(LMCA)闭塞是经皮冠状动脉介入治疗(PCI)时代罕见但严重的情况。更罕见的是 AMI 累及 LMCA 及其分支,如三叉或分叉:这对介入心脏病学家来说是一个挑战,因为它涉及心肌的延伸,伴有心源性休克及其技术困难。三叉状冠状动脉疾病是一种复杂的动脉粥样硬化过程,涉及起源于左主干血管或干的一个或多个侧支的起源,伴有或不伴有 LMCA 本身的受累。在选择性经皮介入治疗中,没有对 LMCA 疾病进行分类或标准化的方法。此外,急性心肌梗死表现为左主干三叉病变似乎更为麻烦,尤其是在年轻患者中。已经描述了少数关于左主干三叉重大病变的 PCI 系列。在此,我们描述了一位成功接受 PCI 治疗的患者,并得到了血管内超声和多层螺旋计算机血管造影(MSCA)的支持,在经过 MSCA 无并发症的随访后,患者现在已经进入了第 9 个月。

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Serum tryptase detected during acute coronary syndrome is significantly related to the development of major adverse cardiovascular events after 2 years.急性冠状动脉综合征期间检测到的血清类胰蛋白酶与2年后主要不良心血管事件的发生显著相关。
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