偏头痛患者的眼震前庭诱发肌源性电位。

Ocular vestibular evoked myogenic potentials in patients with migraine.

机构信息

Department of Neurology, FSM Teaching and Research Hospital, Istanbul, Turkey.

出版信息

Acta Neurol Belg. 2010 Dec;110(4):321-4.

DOI:
Abstract

BACKGROUND

Subclinical cerebello-vestibular impairment has been described in migraine patients.

OBJECTIVES

Our aim was to investigate the presence of subclinical vestibulopathy in migraine patients using ocular vestibular evoked myogenic potentials (oVEMP).

PATIENTS AND METHODS

Forty-three patients suffering from migraine without aura who had no vestibular complaints and 29 healthy controls were included in the study. The responses were recorded from contralateral lower eyelid just above of the inferior oblique muscle during 120 dB click stimulation.

RESULTS

Eight migraine patients (18.6%) disclosed no response. Bilateral or unilateral response rates in the migraine group were 46.5% (n = 20) and 34.9% (n = 15) respectively. In controls, bilateral or unilateral responses could be obtained from 25 (86.7%), and 4 (13.2%) cases, respectively. In migraineurs group mean latencies of N1 and P1 were significantly longer, while N1-P1 amplitudes were found meaningfully lower.

CONCLUSION

These data demonstrate that using oVEMP subclinical vestibular dysfunction can be elicited in migraine patients without vestibular complaints.

摘要

背景

亚临床小脑-前庭功能障碍已在偏头痛患者中被描述。

目的

我们旨在使用眼震电图诱发肌源性电位(oVEMP)来研究偏头痛患者是否存在亚临床前庭病。

患者和方法

本研究纳入了 43 名无先兆偏头痛且无前庭主诉的患者和 29 名健康对照者。在 120dB 点击刺激时,在下斜肌上方的对侧下眼睑记录反应。

结果

8 名偏头痛患者(18.6%)未出现反应。偏头痛组双侧或单侧反应率分别为 46.5%(n=20)和 34.9%(n=15)。在对照组中,25 名(86.7%)和 4 名(13.2%)患者可以获得双侧或单侧反应。偏头痛患者的 N1 和 P1 潜伏期明显延长,而 N1-P1 振幅明显降低。

结论

这些数据表明,在无前庭主诉的偏头痛患者中可以通过 oVEMP 引出亚临床前庭功能障碍。

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