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重大抑郁症对参与毒品法庭的女性使用可卡因和被捕的影响。

Effects of major depression on crack use and arrests among women in drug court.

机构信息

Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02906, USA.

出版信息

Addiction. 2011 Jul;106(7):1279-86. doi: 10.1111/j.1360-0443.2011.03389.x. Epub 2011 Apr 7.

Abstract

AIMS

We examined whether a current major depressive episode (MDE) at baseline predicted crack use and arrests at follow-up among women enrolled in drug court.

DESIGN

Primary analyses used zero-inflated Poisson (ZIP) and zero-inflated negative binomial (ZINB) regression analyses to predict both yes/no and number of (i) days of crack use and (ii) arrests at 4-month follow-up from current (30-day) MDE at baseline. Secondary analyses addressed risk conferred by current versus past MDE at baseline.

SETTING/PARTICIPANTS: Participants were 261 women in drug court.

MEASUREMENTS

MDE was assessed using the Diagnostic Interview Schedule. Days using crack and number of arrests were assessed using the Washington University Risk Behavior Assessment for Women.

FINDINGS

Having a current MDE at baseline predicted likelihood of crack use at follow-up, but not days of crack use among those who used. Current MDE at baseline did not predict presence or number of arrests at the 4-month follow-up. Women with current MDE at baseline were more likely to be using crack at follow-up than were those with recent (31+ days to 12 months) but not current MDE (odds ratio = 5.71); past MDE at baseline did not increase risk of crack use.

CONCLUSIONS

Predictors of any versus no crack use or arrests appear to differ from predictors of frequency of these behaviors. Current major depression, but not past major depression, appears to be associated with increased risk of crack use among women attending drug court.

摘要

目的

本研究旨在探讨基线时的当前重度抑郁发作(MDE)是否会预测参加药物法庭的女性在随访时使用快克和被捕。

设计

主要分析使用零膨胀泊松(ZIP)和零膨胀负二项(ZINB)回归分析来预测基线时当前(30 天)MDE 与 4 个月随访时(i)快克使用天数和(ii)被捕次数之间的关系。次要分析探讨了基线时当前和过去 MDE 所带来的风险。

设置/参与者:参与者为 261 名参加药物法庭的女性。

测量

MDE 使用诊断访谈表进行评估。快克使用天数和被捕次数使用华盛顿大学女性风险行为评估进行评估。

发现

基线时存在当前 MDE 预测了随访时使用快克的可能性,但不能预测使用快克者的快克使用天数。基线时的当前 MDE 并未预测 4 个月随访时的被捕存在或数量。与最近(31 天至 12 个月)但无当前 MDE 的女性相比,基线时患有当前 MDE 的女性在随访时更有可能使用快克(优势比=5.71);过去的 MDE 并未增加快克使用的风险。

结论

任何与无快克使用或被捕的预测因素与这些行为的频率预测因素似乎不同。当前的重度抑郁症,而不是过去的重度抑郁症,似乎与参加药物法庭的女性使用快克的风险增加有关。

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