Psoriasis Research Center, Baylor University Medical Center, Dallas, Texas, USA.
J Am Acad Dermatol. 2011 Jul;65(1):137-74. doi: 10.1016/j.jaad.2010.11.055. Epub 2011 Feb 8.
Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In the first 5 parts of the American Academy of Dermatology Psoriasis Guidelines of Care, we have presented evidence supporting the use of topical treatments, phototherapy, traditional systemic agents, and biological therapies for patients with psoriasis and psoriatic arthritis. In this sixth and final section of the Psoriasis Guidelines of Care, we will present cases to illustrate how to practically use these guidelines in specific clinical scenarios. We will describe the approach to treating patients with psoriasis across the entire spectrum of this fascinating disease from mild to moderate to severe, with and without psoriatic arthritis, based on the 5 prior published guidelines. Although specific therapeutic recommendations are given for each of the cases presented, it is important that treatment be tailored to meet individual patients' needs. In addition, we will update the prior 5 guidelines and address gaps in research and care that currently exist, while making suggestions for further studies that could be performed to help address these limitations in our knowledge base.
银屑病是一种常见的慢性炎症性多系统疾病，主要表现为皮肤和关节病变，影响约 2%的人口。在美国皮肤病学会银屑病治疗指南的前 5 部分中，我们已经提出了支持使用局部治疗、光疗、传统系统药物和生物疗法治疗银屑病和银屑病关节炎患者的证据。在银屑病治疗指南的第六部分，也是最后一部分中，我们将举例说明如何在特定的临床情况下实际应用这些指南。我们将根据之前发表的 5 项指南，描述治疗从轻度到中度到重度、有和没有银屑病关节炎的整个疾病谱中银屑病患者的方法。虽然为每个提出的病例都给出了具体的治疗建议，但根据患者的个体需求来调整治疗方案非常重要。此外，我们将更新之前的 5 项指南，并解决目前存在的研究和护理差距，同时为进一步的研究提供建议，以帮助解决我们知识库中的这些局限性。
