Department of Plastic Surgery, Frenchay Hospital, North Bristol NHS Trust, Bristol BS16 1LE, UK.
J Plast Reconstr Aesthet Surg. 2011 May;64(5):e121-4. doi: 10.1016/j.bjps.2011.01.001.
Familial Partial Lipodystrophy (or Dunnigan-Kobberling syndrome) is characterised by the progressive loss of peripheral subcutaneous fat, with or without truncal involvement. The resultant physical changes in appearance may be dramatic, especially in women, and their psychological impact underestimated. There are limited reports regarding the role of reconstructive procedures to address the physical defects imposed by the various lipodystrophy syndromes, and much of the work to date has focused around facial lipoatrophy in patients with HIV-1 protease inhibitor induced disease. We, however, present a single case report pertaining to the role of breast augmentation in patients with truncal lipoatrophy, as in Familial Partial Lipodystrophy.
家族性部分脂肪营养不良(或邓尼根-科伯林综合征)的特征是外周皮下脂肪逐渐丧失,可能伴有躯干受累。由此导致的身体外观变化可能非常显著,尤其是在女性中,而其心理影响被低估了。关于重建手术在各种脂肪营养不良综合征引起的身体缺陷中的作用的报道有限,迄今为止的大部分工作都集中在 HIV-1 蛋白酶抑制剂诱导疾病患者的面部脂肪萎缩上。然而,我们报告了一个关于乳房增大在躯干脂肪萎缩患者中的作用的病例报告,就像家族性部分脂肪营养不良患者一样。