Departments of Electronics and Physics, University of York, Heslington, York YO1 5DD, United Kingdom.
J Xray Sci Technol. 1989 Jan 1;1(2):143-53. doi: 10.3233/XST-1989-1203.
A direct charge coupled device (CCD) detector has been used to record Laue diffraction data from a protein crystal illuminated with a synchrotron radiation beam of continuous wavelengths 0.2 Å < λ < 2.5 Å. The exposure time used to record the data was 40-80 ms. The point spread factor of the detector was negligible. The sensitivity of CCD detectors at high photon energies is discussed in relation to other electronic area detector schemes. The lack of fine energy resolution of this or any other electronic area detector is not considered a limiting factor because of the high proportion of spots of single wavelength arising from single reciprocal lattice points. A time-resolved study of radiation damage to a crystal of concanavalin A was performed.
已使用直接电荷耦合器件 (CCD) 探测器记录了蛋白质晶体的劳埃衍射数据，该晶体用连续波长 0.2 Å < λ < 2.5 Å 的同步加速器辐射束照射。记录数据所用的曝光时间为 40-80 毫秒。探测器的点扩散函数可以忽略不计。讨论了 CCD 探测器在高光子能量下的灵敏度与其他电子面探测器方案的关系。由于单一倒易点阵点产生的单一波长斑点比例很高，因此这种或任何其他电子面探测器缺乏精细能量分辨率并不被认为是一个限制因素。还对伴刀豆球蛋白 A 晶体的辐射损伤进行了时间分辨研究。
