Can Fam Physician. 1976 Feb;22:42-6.
Certain factors which are major determinants in the survival of the septic patient - age, underlying disease, infecting organism - are beyond the physician's control. Others, however, we can have some impact on. These include initial vigorous supportive treatment, early and appropriate antibiotic administration and timely surgical intervention. In the following discussion current understanding of the pathophysiology of sepsis is outlined, together with a practical approach to the problem of patient management.
某些因素是影响脓毒症患者生存的主要决定因素——年龄、基础疾病、感染病原体——这些因素超出了医生的控制范围。然而,还有一些因素我们可以施加一些影响。这些因素包括初始积极的支持性治疗、早期和适当的抗生素治疗以及及时的手术干预。在下面的讨论中,概述了对脓毒症病理生理学的当前理解,并提出了一种处理患者管理问题的实用方法。