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眼睑基底细胞癌切除不完全意味着肿瘤复发吗?

Does incomplete excision of basal cell carcinoma of the eyelid mean tumor recurrence?

作者信息

Jankovic Irena, Kovacevic Predrag, Visnjic Milan, Jankovic Dimitrije, Binic Ivana, Jankovic Aleksandar

机构信息

Plastic and Reconstructive Surgery Clinic, Clinical Center Nis, Serbia.

出版信息

An Bras Dermatol. 2010 Nov-Dec;85(6):872-7. doi: 10.1590/s0365-05962010000600014.

DOI:10.1590/s0365-05962010000600014
PMID:21308312
Abstract

INTRODUCTION

Basal cell carcinoma is the most common tumor of the eyelid. In this region, reconstruction is complex and damage to healthy tissue should be minimal.

OBJECTIVE

To define the relationship between margin clearance at excision and the recurrence rate of basal cell carcinoma of the eyelid.

METHODS

This prospective study was conducted with 111 patients submitted to surgery for basal cell carcinoma of the eyelid between 2001 and 2003 and followed up for a period of five years. The patients were evaluated according to age, tumor site, recurrence rate and margin clearance at excision.

RESULTS

No significant association was found between incomplete tumor excision and recurrence except in patients under 56 years of age, female patients and in the case of tumors of the medial canthus.

CONCLUSION

A risk of recurrence in incompletely excised basal cell carcinomas of the eyelid was only confirmed in younger patients, females and for tumors of the medial canthus.

摘要

引言

基底细胞癌是眼睑最常见的肿瘤。在该区域,重建过程复杂,对健康组织的损伤应降至最低。

目的

明确眼睑基底细胞癌切除时切缘净距与复发率之间的关系。

方法

本前瞻性研究对2001年至2003年间接受眼睑基底细胞癌手术的111例患者进行,随访五年。根据年龄、肿瘤部位、复发率和切除时的切缘净距对患者进行评估。

结果

除56岁以下患者、女性患者以及内眦部肿瘤外,未发现肿瘤切除不完全与复发之间存在显著关联。

结论

仅在年轻患者、女性患者以及内眦部肿瘤中证实了眼睑基底细胞癌切除不完全存在复发风险。

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Does incomplete excision of basal cell carcinoma of the eyelid mean tumor recurrence?眼睑基底细胞癌切除不完全意味着肿瘤复发吗?
An Bras Dermatol. 2010 Nov-Dec;85(6):872-7. doi: 10.1590/s0365-05962010000600014.
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[Clinical and histologic features of 141 primary basal cell carcinomas of the periocular region and their rate of recurrence after surgical excision].[141例眼周原发性基底细胞癌的临床及组织学特征及其手术切除后的复发率]
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Am J Ophthalmol. 2006 Aug;142(2):293-7. doi: 10.1016/j.ajo.2006.03.055.
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Questioning the work "does an incomplete excision of the eyelid basal cell carcionoma mean tumor recurrence?".质疑“眼睑基底细胞癌切除不完全意味着肿瘤复发吗?”这项研究
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Outcome of 110 basal cell carcinomas of the eyelid treated with frozen section-controlled excision: mean follow-up over 5 years.经冰冻切片控制切除治疗的110例眼睑基底细胞癌的结局:平均随访超过5年。
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Mohs surgery vs primary excision for eyelid BCCs.眼睑基底细胞癌的莫氏手术与原发性切除术对比
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Medial canthus tumor surgery: a prospective study of microscopically controlled excision.内眦肿瘤手术:显微镜控制下切除的前瞻性研究
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Mohs histographic surgery and ophthalmic plastic reconstruction.莫氏组织病理学手术与眼部整形重建
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