Jankovic Irena, Kovacevic Predrag, Visnjic Milan, Jankovic Dimitrije, Binic Ivana, Jankovic Aleksandar
Plastic and Reconstructive Surgery Clinic, Clinical Center Nis, Serbia.
An Bras Dermatol. 2010 Nov-Dec;85(6):872-7. doi: 10.1590/s0365-05962010000600014.
Basal cell carcinoma is the most common tumor of the eyelid. In this region, reconstruction is complex and damage to healthy tissue should be minimal.
To define the relationship between margin clearance at excision and the recurrence rate of basal cell carcinoma of the eyelid.
This prospective study was conducted with 111 patients submitted to surgery for basal cell carcinoma of the eyelid between 2001 and 2003 and followed up for a period of five years. The patients were evaluated according to age, tumor site, recurrence rate and margin clearance at excision.
No significant association was found between incomplete tumor excision and recurrence except in patients under 56 years of age, female patients and in the case of tumors of the medial canthus.
A risk of recurrence in incompletely excised basal cell carcinomas of the eyelid was only confirmed in younger patients, females and for tumors of the medial canthus.
基底细胞癌是眼睑最常见的肿瘤。在该区域,重建过程复杂,对健康组织的损伤应降至最低。
明确眼睑基底细胞癌切除时切缘净距与复发率之间的关系。
本前瞻性研究对2001年至2003年间接受眼睑基底细胞癌手术的111例患者进行,随访五年。根据年龄、肿瘤部位、复发率和切除时的切缘净距对患者进行评估。
除56岁以下患者、女性患者以及内眦部肿瘤外,未发现肿瘤切除不完全与复发之间存在显著关联。
仅在年轻患者、女性患者以及内眦部肿瘤中证实了眼睑基底细胞癌切除不完全存在复发风险。