Carrat F, Ringa V, Blondel B, Bréart G
Maternal and Child Health Epidemiology Research Unit, INSERM, Villejuif, France.
Fetal Diagn Ther. 1990;5(3-4):114-23. doi: 10.1159/000263580.
We studied the fetal and maternal characteristics that affect the diagnosis of intrauterine growth retardation and lead to variations in the sensitivity, specificity and predictive values. The population comprised the 18,166 women who consulted and delivered in two teaching hospitals in Paris from 1978 to 1983. Specificity was lower when a child was born before 37 weeks, with a small weight-for-gestational age, and when the mother had experienced complications during either her obstetric history or current pregnancy. Conversely, sensitivity was higher when these maternal and fetal characteristics were present. Positive predictive values rose in the presence of a risk factor for small-for-dates, but the rise was smaller than would have been expected if sensitivity and specificity had remained at the levels observed in the low-risk group.
我们研究了影响宫内生长迟缓诊断并导致敏感性、特异性和预测值出现差异的胎儿及母体特征。研究人群包括1978年至1983年在巴黎两家教学医院就诊并分娩的18166名女性。当婴儿在37周前出生、出生体重低于孕周预期,以及母亲在既往产科病史或当前妊娠期间出现并发症时,特异性较低。相反,当存在这些母体和胎儿特征时,敏感性较高。在存在小于胎龄风险因素的情况下,阳性预测值会升高,但升高幅度小于在敏感性和特异性保持在低风险组所观察到的水平时的预期升高幅度。