Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20184, USA,
Curr Infect Dis Rep. 2010 Mar;12(2):81-7. doi: 10.1007/s11908-010-0084-5.
Adenovirus plays a significant role in respiratory tract disease in pediatric and adult patients. It has been linked to outbreaks and epidemics in various patient populations, resulting in considerable morbidity and mortality. In this article, we discuss the epidemiology, pathogenesis, respiratory tract illnesses and complications, and roles of potential treatment options. The role of the past oral adenovirus vaccine and the military implications of its withdrawal from routine use in military recruits is discussed as well.
腺病毒在儿科和成年患者的呼吸道疾病中起着重要作用。它与各种患者群体中的暴发和流行有关,导致相当高的发病率和死亡率。在本文中,我们讨论了流行病学、发病机制、呼吸道疾病和并发症,以及潜在治疗选择的作用。还讨论了过去口服腺病毒疫苗的作用以及从军事新兵常规使用中撤出该疫苗的军事意义。