Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University, 660 South Euclid Avenue, Campus Box 8052, St. Louis, MO, 63110, USA,
Curr Infect Dis Rep. 2010 Sep;12(5):368-73. doi: 10.1007/s11908-010-0121-4.
Sepsis and its attendant complications are commonly encountered in the intensive care unit. Early recognition of sepsis is critical because it allows for rapid deployment of a multifaceted resuscitation package. The cornerstones of sepsis management are antibiotic therapy, source control, and hemodynamic resuscitation. In select patients, ancillary therapies are indicated, such as activated protein C, corticosteroids, and glycemic control. Given the complexity of sepsis management, optimal care can be delivered as a bundle-a protocol encompassing the above interventions. The evidence behind the various components of sepsis management are reviewed here.
脓毒症及其伴随的并发症在重症监护病房中很常见。早期识别脓毒症至关重要，因为它可以快速实施多方面的复苏方案。脓毒症管理的基石是抗生素治疗、源头控制和血流动力学复苏。在某些患者中，需要辅助治疗，如活化蛋白 C、皮质类固醇和血糖控制。鉴于脓毒症管理的复杂性，最佳护理可以作为一个包含上述干预措施的方案来提供。本文回顾了脓毒症管理各个组成部分的证据。
