Rodgers B
MRC National Survey of Health and Development, University College London.
Br J Psychiatry. 1990 Oct;157:539-50. doi: 10.1192/bjp.157.4.539.
Childhood precursors of symptoms of depression and anxiety were investigated in a national population sample of over 3000 men and women, aged 36 years. Early-life data had been collected prospectively for all subjects. A number of factors, differing for men and women, were found to be significant predictors of adult disorder. Some factors showed strong effects but tended to apply to relatively few individuals, while other more common circumstances had modest influences. Overall, early environment did not seem to hold great significance for adult affective disorder, although multiple disadvantages had a cumulative deleterious effect. There was little evidence of early benefits being protective.
在一个由36岁的3000多名男性和女性组成的全国性人口样本中，对抑郁和焦虑症状的童年先兆进行了调查。所有受试者的早期生活数据均为前瞻性收集。研究发现，一些男女有别的因素是成人疾病的重要预测指标。一些因素显示出强烈的影响，但往往只适用于相对较少的个体，而其他更常见的情况影响较小。总体而言，早期环境对成人情感障碍似乎没有太大影响，尽管多重不利因素具有累积的有害作用。几乎没有证据表明早期的有益因素具有保护作用。
