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间歇性外斜视患者单侧后徙-切除术复发的预后因素。

Prognostic factors for recurrence with unilateral recess-resect procedure in patients with intermittent exotropia.

机构信息

Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, South Korea.

出版信息

Eye (Lond). 2011 Apr;25(4):449-54. doi: 10.1038/eye.2011.12. Epub 2011 Feb 11.

Abstract

PURPOSE

To evaluate the prognostic factors, particularly age at the time of surgery, for recurrence after unilateral medial rectus resection and lateral rectus recession (R&R) procedures in patients with intermittent exotropia, or X(T).

METHODS

Medical records of 489 subjects who received unilateral R&R procedures with more than 12 months of follow-up were reviewed. The patients' surgical outcomes with a deviation of less than 10 prism diopters (PD) of exotropia and less than 5 PD of esotropia were defined as a success. Outcomes with more than 11 PD of exotropia were designated as recurrences, and those with esotropia of more than 5 PD after 3 months of operation were noted as overcorrection. The prognostic factors for recurrence were analyzed by the multivariate logistic regression test.

RESULTS

Of the 489 subjects, 209 had successful surgical outcomes and 280 had recurrences, whereas overcorrection was not found. Mean age at operation was 8.9 ± 6.5 years, mean preoperative distant X(T) size was 32.9 ± 6.0 PD, and mean follow-up period was 27.5 ± 17.9 months. On the basis of the survival analysis in which survival represented time of recurrence, the mean duration was 31.2 ± 1.7 months. Age at onset, age at surgery, and immediate postoperative alignment proved to be significant factors influencing a favorable outcome by multivariate logistic regression analysis (P<0.05). However, gender, family history, and preoperative deviation size were not significantly predictive of success (P>0.05).

CONCLUSION

In unilateral R&R procedures, increasing patient age at the time of surgery was associated with lower recurrence rates. Recurrence rates also increased with the immediate postoperative angle and with the postoperative angle of deviation at 1, 3, 6, and 12 months.

摘要

目的

评估单侧内直肌切除术和外直肌后退术(R&R)后间歇性外斜视(X(T))患者复发的预后因素,特别是手术时的年龄。

方法

回顾了 489 例接受单侧 R&R 手术且随访时间超过 12 个月的患者的病历。将斜视小于 10 棱镜度(PD)和内斜视小于 5 PD 的患者手术结果定义为成功。将斜视大于 11 PD 的患者定为复发,将术后 3 个月内斜视大于 5 PD 的患者定为过矫。采用多变量逻辑回归检验分析复发的预后因素。

结果

489 例患者中,209 例手术结果成功,280 例复发,无过矫。手术时的平均年龄为 8.9 ± 6.5 岁,术前远距 X(T)大小平均为 32.9 ± 6.0 PD,平均随访时间为 27.5 ± 17.9 个月。基于以复发时间为代表的生存分析,平均持续时间为 31.2 ± 1.7 个月。多变量逻辑回归分析显示,发病年龄、手术年龄和即时术后眼位是影响手术结果的显著因素(P<0.05)。然而,性别、家族史和术前斜视大小对手术结果无显著预测作用(P>0.05)。

结论

在单侧 R&R 手术中,患者手术时的年龄越大,复发率越低。即时术后斜视角度和术后 1、3、6 和 12 个月的斜视角度越大,复发率也越高。

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