Lawrence B, Santen R J, Lipton A, Harvey H A, Hamilton R, Mercurio T
Cancer Treat Rep. 1978 Oct;62(10):1581-3.
Aminoglutethimide is an investigational agent of proven benefit in the treatment of metastatic breast carcinoma. We report herein a case of aminoglutethimide-induced pancytopenia complicated by bleeding and gram-negative septicemia. Severe pancytopenia is a rare but important side effect of this new drug and is rapidly reversible when the agent is withdrawn.
氨鲁米特是一种已证实对转移性乳腺癌治疗有益的研究性药物。我们在此报告一例氨鲁米特诱发的全血细胞减少症，并发出血和革兰氏阴性菌败血症。严重全血细胞减少是这种新药罕见但重要的副作用，停药后可迅速逆转。
