Kazandi M, Zeybek B, Terek M C, Zekioglu O, Ozdemir N, Oztekin K
Department of Obstetrics and Gynecology, Ege University School of Medicine, Izmir, Turkey.
Eur J Gynaecol Oncol. 2010;31(6):719-21.
Adenomyosis is defined by the presence of endometrial tissue (glands and stroma) within the myometrium and malignant transformation of adenomyosis in premenopausal women with normal endometrium is extremely rare. Adenocarcinomas arising within adenomyosis need to be distinguished from endometrial carcinomas which arise from the eutopic endometrium, then extend into preexisting adenomyosis of the uterine wall. We report a case of grade 2 endometrioid adenocarcinoma arising from an adenomyotic focus in the uterus.
子宫腺肌病是由子宫肌层内存在子宫内膜组织(腺体和间质)所定义的,在子宫内膜正常的绝经前女性中,子宫腺肌病发生恶性转化极为罕见。子宫腺肌病内发生的腺癌需要与起源于正常位置子宫内膜、然后蔓延至子宫壁原有子宫腺肌病的子宫内膜癌相鉴别。我们报告一例起源于子宫腺肌病病灶的2级子宫内膜样腺癌病例。