Arzumanov Iu L, Abakumova A A, Borisova E V, Adamova A V
Zh Nevrol Psikhiatr Im S S Korsakova. 2010;110(5 Pt 2):15-8.
Eighty patients with heroin addiction, aged from 15 to 20 years (most of them over the age of 16), were examined. The duration of illness was from 6 months to 3 years. The examination was conducted 2-3 weeks after arresting of withdrawal syndrome. In that period, patients had different mental disorders: depressive-dysphoric, neurosis-like, anxiety-hypochondriac, hysteriform and others. The aim of the examination was to find peculiarities of functioning of different cortical regions in the process of appraisal of conscious and unconscious stimuli using the method of visual evoked potentials with P300 recording. Stimuli were words highlighted on the screen--indifferent and potentially significant for a patient (e.g. heroin). The stimulus related to the dominating motivation caused in patients the higher diffuse cortical activation on the unconscious level compared to non-targeted stimuli.
对80名年龄在15至20岁(其中大多数超过16岁)的海洛因成瘾者进行了检查。病程为6个月至3年。检查在戒断综合征戒断2至3周后进行。在此期间,患者有不同的精神障碍:抑郁烦躁型、神经症样、焦虑疑病型、癔症样等。检查的目的是使用记录P300的视觉诱发电位方法,找出在评估有意识和无意识刺激过程中不同皮质区域的功能特点。刺激物是屏幕上突出显示的单词——对患者来说无关紧要的和潜在重要的(如海洛因)。与主导动机相关的刺激在无意识水平上比非目标刺激在患者中引起更高的弥漫性皮质激活。