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[药物给药的解剖生理学基础。剂型与给药途径]

[Anatomophysiological bases of drug administration. Dosage forms and routes of administration].

作者信息

Carillo Norte Juan Antonio, Gañán Presmanes Yolanda

机构信息

Departamento de Terapéutica Médico-Quirúrgica, Facultad de Medicina, Universidad de Extremadura.

出版信息

Rev Enferm. 2010 Dec;33(12):28-32, 35-9.

Abstract

The administration of the right dose to the right patient is of paramount importance to obtain an optimal drug response within the scope of clinical pharmacology and tailored medicine. The marketing of safer and more efficient drug entities, along with the development of new drug administration devices provide a major boost for the diagnosis and treatment of diseases, beyond our imagination. However dose adjustment is not enough to produced the desired effect, and drug therapy should include an appropriate route of drug administration. Currently, there are many different and sophisticated methods to incorporate drugs into the patients that nurses should be familiar with. When there is no contraindication, oral route of drug administration is of choice and most frequently used as a physiological pathway of drug intake.

摘要

给合适的患者使用合适的剂量对于在临床药理学和精准医学范围内获得最佳药物反应至关重要。更安全、更高效药物实体的上市,以及新给药装置的开发,为疾病的诊断和治疗带来了超乎想象的巨大推动。然而,仅调整剂量不足以产生预期效果,药物治疗应包括合适的给药途径。目前,有许多不同且复杂的方法将药物输送给患者,护士应熟悉这些方法。在没有禁忌证的情况下,口服给药途径是首选且最常被用作药物摄入的生理途径。

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