孤立同种异体移植输尿管中的输尿管排斥反应。
Ureteral rejection in isolated allograft ureter.
机构信息
McGuire Veterans Administration Hospital, Virginia, USA.
出版信息
Urology. 1974 Jul;4(1):37-9. doi: 10.1016/0090-4295(74)90104-6.
PMID:21322980
Abstract
Ureteral rejection has been studied in the dog utilizing the isolated transplanted ureter technique. While on adequate immunosuppressive therapy, the allograft ureter remains functionally and histologically normal. When the drugs are discontinued, progressive destructive changes occur within the ureteral wall. As the muscle wall is destroyed the rejection process becomes irreversible. This process helps explain some of the findings seen during clinical renal transplantation.
摘要
输尿管排斥反应已在狗中利用孤立移植输尿管技术进行了研究。在充分的免疫抑制治疗下，同种异体输尿管在功能和组织学上保持正常。当停止使用药物时，输尿管壁内会发生进行性破坏性变化。随着肌肉壁的破坏，排斥过程变得不可逆转。这一过程有助于解释临床肾移植中观察到的一些发现。
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引用本文的文献
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