Kondo T
National Institute for Basic Biology, Okazaki, Japan.
J Biol Rhythms. 1990 Fall;5(3):187-94. doi: 10.1177/074873049000500302.
The period of the circadian rhythm of uptake of K+ by Lemna gibba strain G3 (duckweed), cultured in a flow medium, was shortened by continuous application of 0.5 mM tetraethylammonium chloride (TEA), which functions as a K+ channel blocker in both animal and plant cells. Other quaternary ammonium ions shortened the period of the rhythm in direct proportion to their ability to block K+ channels in cells of the nervous system. Ca2+ appears to be specific in its ability to antagonize this action of TEA and of its analogues.
在流动培养基中培养的浮萍（Lemna gibba strain G3）对钾离子（K⁺）吸收的昼夜节律周期，会因持续施加0.5 mM的四乙铵氯化物（TEA）而缩短，TEA在动物和植物细胞中均作为K⁺通道阻滞剂发挥作用。其他季铵离子缩短节律周期的程度与其阻断神经系统细胞中K⁺通道的能力成正比。钙离子（Ca²⁺）似乎在拮抗TEA及其类似物的这一作用方面具有特异性。
