Department of Orthopedic Surgery, Kishiwada City Hospital, 1001, Gakuhara-tyo, Kishiwada, Osaka, 596-8501, Japan.
Mod Rheumatol. 2011 Oct;21(5):514-7. doi: 10.1007/s10165-011-0424-9. Epub 2011 Feb 18.
We report a patient with rheumatoid factor-positive polyarthritis-type juvenile idiopathic arthritis (JIA) in whom clinical remission was achieved within 10 months after the start of methotrexate (MTX) therapy, and systemic repair of bone erosion was noted 8 months after clinical remission. These results indicate that even in cases of active JIA with the development of bone erosion, continuation of MTX therapy after the achievement of clinical remission can improve the prognosis, including repair of bone destruction.
我们报告了一例类风湿因子阳性的多关节炎型幼年特发性关节炎（JIA）患者，该患者在接受甲氨蝶呤（MTX）治疗后 10 个月内达到临床缓解，并且在临床缓解后 8 个月内观察到骨侵蚀的系统修复。这些结果表明，即使在出现骨侵蚀的活动性 JIA 病例中，在达到临床缓解后继续接受 MTX 治疗也可以改善预后，包括修复骨破坏。
