Department of Anesthesiology, Nara Medical University, Kashihara, Nara, Japan.
J Neurosurg. 2011 Jun;114(6):1731-5. doi: 10.3171/2011.1.JNS101326. Epub 2011 Feb 18.
Recent evidence has indicated that the efficacy of the epidural blood patch (EBP) in the treatment of spontaneous CSF hypovolemia (SCH) is still limited. Therefore, further improvement of the EBP technique is an important clinical challenge. The authors describe a series of cases of SCH treated with fluoroscopically guided placement of an EBP and followed up with subsequent spinal CT scans.
Thirteen patients with SCH that was proven on CT myelography studies underwent epidural puncture under fluoroscopic guidance and received an injection of a mixture of contrast medium and autologous blood. Contrast medium was injected to cover the area of CSF leakage during EBP guided by fluoroscopy, and the spread of the blood was subsequently evaluated using spinal CT scanning. If the amount of blood injected was insufficient to cover the leakage area, a second EBP was performed at a later date.
At the first EBP procedure, a mixture with a mean volume of 9.4 ml (range 3-20 ml) was injected, and subsequent spinal CT scans revealed contrast enhancement in the desired epidural space in 12 of 13 patients. In 2 patients, a second EBP was required because of insufficient coverage of the leakage area or delayed recurrence of headache. In all patients, a complete recovery from orthostatic headache was obtained after the last EBP.
The results indicated that fluoroscopically guided EBP and subsequent spinal CT scans may provide a highly effective therapy in patients with SCH proven on CT myelography studies.
最近的证据表明,硬膜外血贴(EBP)治疗自发性脑脊液(CSF)低容量(SCH)的疗效仍然有限。因此,进一步改进 EBP 技术是一个重要的临床挑战。作者描述了一系列经 CT 脊髓造影证实的 SCH 患者,这些患者接受了荧光引导下 EBP 定位,并随后进行了脊髓 CT 扫描。
13 例 SCH 患者在荧光引导下进行硬膜外穿刺,接受造影剂和自体血混合物的注射。在 EBP 过程中,根据荧光透视引导注入造影剂,以覆盖 CSF 漏出区域,随后使用脊髓 CT 扫描评估血液的扩散情况。如果注射的血量不足以覆盖漏出区域,则在以后的日期进行第二次 EBP。
在第一次 EBP 操作中,注入了平均体积为 9.4 毫升(范围 3-20 毫升)的混合物,随后的脊髓 CT 扫描显示 13 例患者中有 12 例期望的硬膜外间隙有造影剂增强。由于漏出区域覆盖不足或头痛延迟复发,2 例患者需要进行第二次 EBP。所有患者在最后一次 EBP 后均完全缓解直立性头痛。
结果表明,荧光引导下 EBP 和随后的脊髓 CT 扫描可能为经 CT 脊髓造影证实的 SCH 患者提供一种非常有效的治疗方法。