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新生儿臂丛神经麻痹的病因。

Causes of neonatal brachial plexus palsy.

作者信息

Alfonso Daniel T

机构信息

Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, NYU Langone Medical Center, New York, NY, USA.

出版信息

Bull NYU Hosp Jt Dis. 2011;69(1):11-6.

Abstract

The causes of brachial plexus palsy in neonates should be classified according to their most salient associated feature. The causes of brachial plexus palsy are obstetrical brachial plexus palsy, familial congenital brachial plexus palsy, maternal uterine malformation, congenital varicella syndrome, osteomyelitis involving the proximal head of the humerus or cervical vertebral bodies, exostosis of the first rib, tumors and hemangioma in the region of the brachial plexus, and intrauterine maladaptation. Kaiser Wilhelm syndrome, neonatal brachial plexus palsy due to placental insufficiency, is probably not a cause of brachial plexus palsy. Obstetrical brachial plexus palsy, the most common alleged cause of neonatal brachial plexus palsy, occurs when the forces generated during labor stretch the brachial plexus beyond its resistance. The probability of obstetrical brachial plexus palsy is directly proportional to the magnitude, acceleration, and cosine of the angle formed by the direction of the vector of the stretching force and the axis of the most vulnerable brachial plexus bundle, and inversely proportional to the resistance of the must vulnerable brachial plexus bundle and of the shoulder girdle muscles, joints, and bones. Since in most nonsurgical cases neither the contribution of each of these factors to the production of the obstetrical brachial plexus palsy nor the proportion of traction and propulsion contributing to the stretch force is known, we concur with prior reports that the term of obstetrical brachial plexus palsy should be substituted by the more inclusive term of birth-related brachial plexus palsy.

摘要

新生儿臂丛神经麻痹的病因应根据其最显著的相关特征进行分类。臂丛神经麻痹的病因包括产伤性臂丛神经麻痹、家族性先天性臂丛神经麻痹、母体子宫畸形、先天性水痘综合征、累及肱骨近端或颈椎体的骨髓炎、第一肋外生骨疣、臂丛神经区域的肿瘤和血管瘤以及子宫内适应不良。可能并非臂丛神经麻痹病因的“凯泽·威廉综合征”是因胎盘功能不全导致的新生儿臂丛神经麻痹。产伤性臂丛神经麻痹是新生儿臂丛神经麻痹最常见的所谓病因,发生在分娩过程中产生的力量将臂丛神经拉伸至其耐受极限时。产伤性臂丛神经麻痹的发生概率与拉伸力矢量方向与最易受损臂丛神经束轴所形成角度的大小、加速度及余弦值成正比,与最易受损臂丛神经束以及肩胛带肌肉、关节和骨骼的抵抗力成反比。由于在大多数非手术病例中,这些因素中每一个对产伤性臂丛神经麻痹形成的作用以及拉伸力中牵引和推进力所占比例均不明确,我们赞同先前的报告,即应将“产伤性臂丛神经麻痹”这一术语替换为涵盖范围更广的“出生相关臂丛神经麻痹”。

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