Department of Dermatology, Sir Charles Gairdner Hospital, Nedlands, Australia.
Australas J Dermatol. 2011 Feb;52(1):e5-7. doi: 10.1111/j.1440-0960.2009.00614.x.
Bowel bypass syndrome, also known as bowel-associated dermatitis arthritis syndrome, has been described after a range of intestinal bypass procedures. With the increasing trend in laparoscopic gastric bypass surgery, we report an interesting case of bowel-associated dermatitis arthritis syndrome that developed 12 months following this procedure. A 49-year-old woman presented with ulcerating lesions and pustules on the upper and lower limbs, polyarthralgia, fevers and joint effusions. Before the development of these symptoms she was well, with no significant past medical or family history. A skin biopsy taken from the left shin showed superficial to mid-dermal neutrophilic dermatosis, consistent with bowel-associated dermatitis arthritis syndrome. The patient received corticosteroids, antibiotics and colchicine treatment, with control of disease after continuing with colchicine. This case may illustrate another possible complication following bariatric surgery. The significant time period between the initial surgery and the development of bowel-associated dermatitis arthritis syndrome may mean that more cases of this condition will continue to emerge.
肠旁路综合征,也称为肠相关性皮炎关节炎综合征,在一系列肠旁路手术后有过描述。随着腹腔镜胃旁路手术的增加趋势,我们报告了一例有趣的肠相关性皮炎关节炎综合征病例,该病例发生在该手术后 12 个月。一位 49 岁女性出现上肢和下肢溃疡性病变和脓疱、多发性关节炎、发热和关节积液。在出现这些症状之前,她身体状况良好,没有明显的既往病史或家族病史。从左小腿取的皮肤活检显示浅至中真皮中性粒细胞性皮炎,符合肠相关性皮炎关节炎综合征。患者接受了皮质类固醇、抗生素和秋水仙碱治疗,继续使用秋水仙碱后病情得到控制。该病例可能说明了减肥手术后的另一种可能并发症。初始手术与肠相关性皮炎关节炎综合征之间的显著时间间隔可能意味着这种疾病的更多病例将继续出现。