狒狒（狒狒属）的先天性异常。
Congenital anomalies in the baboon (Papio spp.).
作者信息
Fox Benjamin, Owston Michael A, Kumar Shyamesh, Dick Edward J
机构信息
Southwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX 78245-0549, USA.
出版信息
J Med Primatol. 2011 Oct;40(5):357-63. doi: 10.1111/j.1600-0684.2011.00472.x. Epub 2011 Feb 21.
BACKGROUND
A comprehensive survey of the prevalence of congenital anomalies in baboons has not been previously reported. We report the congenital anomalies observed over a 26-year period in a large captive baboon colony.
METHODS
A computer search was performed for all baboon congenital anomalies identified at necropsy and recorded on necropsy submissions.
RESULTS
We identified 198 congenital anomalies in 166 baboons from 9972 necropsies (1.66% of total necropsies). The nervous, urogenital, musculoskeletal, and cardiovascular systems were most commonly affected. The most common organs affected were the brain, bone, heart, testicle, kidney, penis, aorta, and skeletal muscle. The most frequent congenital anomalies were blindness, seizures, and hydrocephalus.
CONCLUSIONS
The baboon has an overall frequency of congenital anomalies similar to humans and other non-human primates. Although the most frequently affected systems are similar, congenital anomalies involving the digestive system appear to be less common in the baboon.
背景
此前尚未有关于狒狒先天性异常患病率的全面调查报道。我们报告了在一个大型圈养狒狒群体中26年间观察到的先天性异常情况。
方法
对尸检时确定并记录在尸检报告中的所有狒狒先天性异常进行计算机检索。
结果
我们从9972次尸检中在166只狒狒身上发现了198例先天性异常（占总尸检数的1.66%）。神经、泌尿生殖、肌肉骨骼和心血管系统最常受到影响。受影响最常见的器官是脑、骨、心脏、睾丸、肾脏、阴茎、主动脉和骨骼肌。最常见的先天性异常是失明、癫痫发作和脑积水。
结论
狒狒先天性异常的总体发生率与人类和其他非人类灵长类动物相似。虽然最常受影响的系统相似，但涉及消化系统的先天性异常在狒狒中似乎不太常见。
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