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根治性肾切除术及下腔静脉血栓切除术:低手术量医疗机构的治疗结果

Radical nephrectomy and inferior vena caval thrombectomy: outcomes in a lower volume practice.

作者信息

Calhoun John B, Merchen Todd D, Brown James A

机构信息

Department of Surgery, Medical College of Georgia, Augusta, USA.

出版信息

Can J Urol. 2011 Feb;18(1):5537-41.

Abstract

INTRODUCTION

Surgical volume correlates with improved outcomes for some complex urologic procedures. We reviewed the outcomes of a lower volume practice (1-2 cases per year) experience with radical nephrectomy with infra/retrohepatic vena caval thrombectomy (RNCT).

METHODS

We retrospectively reviewed 10 patients who underwent RNCT performed by a single surgeon at a single state institution over 7 years (2002-2009). Patient demographics, presenting symptoms, preoperative imaging, intraoperative findings, pathology, hospital course, outcomes, level of caval involvement, renal artery embolization, liver mobilization, blood loss, transfusion requirements and follow up times were recorded.

RESULTS

Median patient BMI (n = 8) was 25.7 (18.3-31.9). Eight patients underwent renal artery embolization prior to RNCT. A vascular or liver surgeon assisted in all 10 RNCT cases. Six thrombi were infrahepatic and four were retrohepatic requiring liver mobilization. Median operative time was 340 minutes (220-480) with a median vena cava clamp time of 17 minutes (11-22). Eight (80%) patients required intraoperative transfusion. Median pathologic tumor size was 9.5 cm (range 6-21). Median hospital stay was 7.5 days (5-15). Four patients had complications including colonic mesenteric rent (n = 2), abscess (n = 1), retroperitoneal hematoma (n = 1), distal pancreatic injury (n = 1), and splenic capsular tear (n = 1). One patient had postoperative liver metastasis. Two patients died from postoperative metastasis, at 5 months and 11 months.

CONCLUSIONS

RNCT can be performed, with the assistance of a vascular/liver transplant surgeon, for an infrahepatic or retrohepatic thrombus satisfactorily in a lower volume practice.

摘要

引言

对于某些复杂的泌尿外科手术,手术量与更好的治疗效果相关。我们回顾了一家手术量较低(每年1 - 2例)的机构进行根治性肾切除术联合肝下/肝后腔静脉血栓切除术(RNCT)的治疗效果。

方法

我们回顾性分析了7年间(2002 - 2009年)在一家州立机构由一名外科医生实施RNCT的10例患者。记录患者的人口统计学资料、症状表现、术前影像学检查、术中发现、病理情况、住院过程、治疗效果、腔静脉受累程度、肾动脉栓塞、肝脏游离情况、失血量、输血需求及随访时间。

结果

患者中位体重指数(n = 8)为25.7(18.3 - 31.9)。8例患者在RNCT术前接受了肾动脉栓塞。所有10例RNCT手术均有血管外科或肝脏外科医生协助。6例血栓位于肝下,4例位于肝后,后者需要游离肝脏。中位手术时间为340分钟(220 - 480),中位腔静脉阻断时间为17分钟(11 - 22)。8例(80%)患者术中需要输血。病理肿瘤中位大小为9.5 cm(范围6 - 21)。中位住院时间为7.5天(5 - 15)。4例患者出现并发症,包括结肠系膜撕裂(n = 2)、脓肿(n = 1)、腹膜后血肿(n = 1)、远端胰腺损伤(n = 1)和脾包膜撕裂(n = 1)。1例患者术后出现肝转移。2例患者术后因转移死亡,分别在术后5个月和11个月。

结论

在血管/肝脏移植外科医生的协助下,对于手术量较低的机构,肝下或肝后血栓的RNCT手术可以令人满意地完成。

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