Zucca M, Cenna S, Berzioli S, Gariglio M, Fagnoni V
Istituto di Microbiologia, Università di Torino.
G Batteriol Virol Immunol. 1990 Jan-Dec;83(1-12):108-17.
The central role of Streptococcus mutans in the pathogenesis of caries is universally recognized. In this article we discuss bacterial metabolism relevant to plaque formation and enamel destruction, and review current methods and new prospects in caries prophylaxis: the use of fluorine, possible substitutes for sucrose, active and passive immunoprophylaxis, teeth colonization with non-cariogenic strains of S. mutans. No one of these methods can be considered a definitive solution for every caries problem, but short term major achievements can be reasonably attained by ongoing field research.
变形链球菌在龋齿发病机制中的核心作用已得到普遍认可。在本文中,我们讨论了与牙菌斑形成和牙釉质破坏相关的细菌代谢,并综述了当前龋齿预防的方法和新前景:氟的使用、蔗糖的可能替代品、主动和被动免疫预防、用非致龋性变形链球菌菌株定植牙齿。这些方法中没有一种能被视为解决所有龋齿问题的最终方案,但通过正在进行的实地研究可以合理地取得短期的重大成果。