Vásquez Tineo S I, García lonso M P, Mendoza Paulini A, Paniagua Correa C, Balsa Bretón M A, Mariana Monguía A, Castillejos Rodríguez L, Ortega Valle A, Penín Gonzalez F J, Pey Illera C
Servicio de Medicina Nuclear, Hospital Universitario de Getafe, Madrid, España.
Rev Esp Med Nucl. 2011 Sep-Oct;30(5):311-3. doi: 10.1016/j.remn.2010.09.007. Epub 2011 Feb 22.
Intrathoracic splenosis is a generally asymptomatic entity incidentally diagnosed after the completion of an Rx, CT scan or MRI for another reason. The performance of scintigraphy with (99m)Tc-labelled heat-denatured erythrocytes allows the noninvasive diagnosis of this entity and avoids more aggressive diagnostic techniques such as FNAP or thoracotomy. Because this splenic tissue may be partially or fully functioning and therefore may have some beneficial immune function for the patient, the management of this entity should be conservative. Radioisotopic scintigraphy with (99m)Tc labelled heat-denatured erythrocytes is the technique with the greatest specificity in the demonstration of splenic tissue. The presence of subpleural pulmonary nodules, associated or not with intra-abdominal nodules, together with the existence of previous partial or total splenectomy, traumatic or not, with or without associated rupture of the diaphragm, should raise suspicion of the presence of intrathoracic splenosis.
胸腔内脾组织异位通常是一种无症状的情况，在因其他原因进行X线检查、CT扫描或MRI检查后偶然被诊断出来。使用（99m）Tc标记的热变性红细胞进行闪烁扫描可对该病症进行无创诊断，避免采用更具侵入性的诊断技术，如细针穿刺抽吸活检（FNAP）或开胸手术。由于这种脾组织可能部分或完全发挥功能，因此可能对患者具有一定有益的免疫功能，对此病症的处理应采取保守治疗。用（99m）Tc标记的热变性红细胞进行放射性核素闪烁扫描是显示脾组织特异性最高的技术。存在与腹腔内结节相关或不相关的胸膜下肺结节，以及既往有过部分或全脾切除术（无论是否有创伤，有无膈肌破裂），均应怀疑存在胸腔内脾组织异位。
