Neuroradiology, Amiens University Hospital, 1 Place Victor Pauchet, 80054 Amiens Cedex 1, France.
Eur J Radiol. 2012 Mar;81(3):522-7. doi: 10.1016/j.ejrad.2011.01.076. Epub 2011 Feb 21.
Our purpose was to differentiate glioblastoma from metastasis using a single dynamic MR sequence to assess perfusion and permeability parameters. 24 patients with glioblastoma or cerebral metastasis with peritumoral oedema were recruited and explored with a 3T MR unit. Post processing used DPTools software. Regions of interest were drawn around contrast enhancement to assess relative cerebral blood volume and permeability parameters. Around the contrast enhancement Glioblastoma present high rCBV with modification of the permeability, metastasis present slight modified rCBV without modification of permeability. In conclusion, peritumoral T2 hypersignal exploration associating morphological MR and functional MR parameters can help to differentiate cerebral metastasis from glioblastoma.
我们的目的是使用单一的动态磁共振序列来区分胶质母细胞瘤和转移瘤，以评估灌注和通透性参数。我们招募了 24 名患有胶质母细胞瘤或脑转移瘤伴瘤周水肿的患者，并在 3T MR 仪上进行了探索。使用 DPTools 软件进行后处理。在对比增强周围绘制感兴趣区域，以评估相对脑血容量和通透性参数。胶质母细胞瘤在对比增强周围呈现高 rCBV，并伴有通透性改变，而转移瘤则呈现轻微的 rCBV 改变，而通透性不变。总之，瘤周 T2 高信号的探索结合形态学和功能磁共振参数有助于区分脑转移瘤和胶质母细胞瘤。
