Department of Chemistry, Photonics Center, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
Org Lett. 2011 Mar 18;13(6):1346-9. doi: 10.1021/ol200032f. Epub 2011 Feb 21.
Irradiation of 1,2-dimethyl-3-hydroxyquinolinone (DMQ) leads to excited state intramolecular proton transfer (ESIPT) generating a 3-oxidoquinolinium species which undergoes [3 + 2] photocycloaddition with dipolarophiles. A parallel, fluorescence quenching assay using a microplate format has been developed to evaluate fluorescence quenching of this species with a range of dipolarophiles.
1,2-二甲基-3-羟基喹啉酮(DMQ)经辐照后会发生激发态分子内质子转移(ESIPT),生成 3-氧代喹啉鎓物种,后者可与偶极子发生[3+2]光环加成反应。本研究开发了一种平行荧光猝灭分析方法,采用微孔板格式,评估了一系列偶极子对该物种荧光猝灭的效果。