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本文引用的文献

1
Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation.3-羟基黄酮的仿生光环加成反应：作为真核生物翻译抑制剂的洛卡酸酯衍生物的合成与评价
Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6533-8. doi: 10.1002/anie.201003212.
2
A fluorogenic aldehyde bearing a 1,2,3-triazole moiety for monitoring the progress of aldol reactions.一种带有1,2,3-三唑部分的荧光醛，用于监测羟醛反应的进程。
J Org Chem. 2009 Mar 20;74(6):2417-24. doi: 10.1021/jo900013w.
3
Enantioselective synthesis of the complex rocaglate (-)-silvestrol.复杂的罗卡汀（-）-银叶醇的对映选择性合成。
Angew Chem Int Ed Engl. 2007;46(41):7831-4. doi: 10.1002/anie.200702707.
4
Steric control of the excited-state intramolecular proton transfer in 3-hydroxyquinolones: steady-state and time-resolved fluorescence study.3-羟基喹诺酮类化合物激发态分子内质子转移的空间控制：稳态和时间分辨荧光研究
J Phys Chem A. 2007 Sep 20;111(37):8986-92. doi: 10.1021/jp071075t. Epub 2007 Aug 24.
5
Benchtop monitoring of reaction progress via visual recognition with a handheld UV lamp: in situ monitoring of boronic acids in the Suzuki-Miyaura reaction.通过手持紫外灯进行视觉识别对反应进程进行台式监测：铃木-宫浦反应中硼酸的原位监测。
Org Lett. 2007 Jan 4;9(1):137-9. doi: 10.1021/ol062802q.
6
Modulation of dual fluorescence in a 3-hydroxyquinolone dye by perturbation of its intramolecular proton transfer with solvent polarity and basicity.通过溶剂极性和碱性对3-羟基喹诺酮染料分子内质子转移的扰动来调制其双重荧光。
Photochem Photobiol Sci. 2006 Nov;5(11):1038-44. doi: 10.1039/b610054f. Epub 2006 Aug 16.
7
Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels-Alder cycloadditions.喜树碱C20-二萜生物碱的高效合成途径。通过氧化异喹啉鎓-1,3-偶极环加成和烯胺-狄尔斯-阿尔德环加成反应简洁合成去甲喜树碱。
J Am Chem Soc. 2006 Jul 12;128(27):8734-5. doi: 10.1021/ja0625430.
8
Enantioselective photocycloaddition mediated by chiral Brønsted acids: asymmetric synthesis of the rocaglamides.手性布朗斯特酸介导的对映选择性光环加成反应：洛卡酰胺的不对称合成
J Am Chem Soc. 2006 Jun 21;128(24):7754-5. doi: 10.1021/ja062621j.
9
A biomimetic approach to the rocaglamides employing photogeneration of oxidopyryliums derived from 3-hydroxyflavones.一种利用从3-羟基黄酮衍生的氧化吡啶鎓的光生作用来合成rocaglamides的仿生方法。
J Am Chem Soc. 2004 Oct 27;126(42):13620-1. doi: 10.1021/ja044798o.
10
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching.通过荧光猝灭发现并表征用于叠氮化物-炔烃环加成反应的催化剂
J Am Chem Soc. 2004 Aug 4;126(30):9152-3. doi: 10.1021/ja048425z.

ESIPT 介导的 3-羟基喹啉酮的光环加成反应：反应筛选的荧光猝灭测定法的建立。

ESIPT-mediated photocycloadditions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for reaction screening.

机构信息

Department of Chemistry, Photonics Center, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.

出版信息

Org Lett. 2011 Mar 18;13(6):1346-9. doi: 10.1021/ol200032f. Epub 2011 Feb 21.

DOI:10.1021/ol200032f
PMID:21338078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3055927/
Abstract

Irradiation of 1,2-dimethyl-3-hydroxyquinolinone (DMQ) leads to excited state intramolecular proton transfer (ESIPT) generating a 3-oxidoquinolinium species which undergoes [3 + 2] photocycloaddition with dipolarophiles. A parallel, fluorescence quenching assay using a microplate format has been developed to evaluate fluorescence quenching of this species with a range of dipolarophiles.

摘要

1,2-二甲基-3-羟基喹啉酮（DMQ）经辐照后会发生激发态分子内质子转移（ESIPT），生成 3-氧代喹啉鎓物种，后者可与偶极子发生[3+2]光环加成反应。本研究开发了一种平行荧光猝灭分析方法，采用微孔板格式，评估了一系列偶极子对该物种荧光猝灭的效果。