Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210097, China.
Org Lett. 2011 Mar 18;13(6):1286-9. doi: 10.1021/ol103075n. Epub 2011 Feb 21.
Pd(II)-catalyzed aromatic C-H bond activation using cyano as a directing group was carried out in TFA medium. Biphenyl-2-carbonitrile derivatives were therefore synthesized from aryl nitriles and aryl halides in moderate to good yields.
Pd(II) 催化的使用氰基作为导向基团的芳基 C-H 键活化反应在 TFA 介质中进行。因此，芳基腈和芳基卤化物可以中等至良好的产率合成联苯-2-腈衍生物。
