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儿童胃肠道系统畸形与先天性心脏缺陷有关。

Gastrointestinal system malformations in children are associated with congenital heart defects.

作者信息

Orün Utku Arman, Bilici Meki, Demirçeken Fulya G, Tosun Mahya, Ocal Burhan, Cavuşoğlu Yusuf Hakan, Erdoğan Derya, Senocak Filiz, Karademir Selmin

机构信息

Clinic of Pediatric Cardiology, Department of Pediatric Cardiology, Faculty of Medicine, Fatih University, Ankara, Turkey.

出版信息

Anadolu Kardiyol Derg. 2011 Mar;11(2):146-9. doi: 10.5152/akd.2011.034. Epub 2011 Feb 23.

DOI:10.5152/akd.2011.034
PMID:21342865
Abstract

OBJECTIVE

To determine the frequency of congenital heart defects (CHD) in children with gastrointestinal malformations (GISM) and mortality rates in patients with GISM.

METHODS

Two hundred and forty two consecutive children patients with GISM followed up in Pediatric Surgery Clinics of our hospital were examined for cardiovascular anomaly by the Department of Pediatric Cardiology, and the CHD incidence was investigated by examining the records of the patients retrospectively. Chi-square test was used for the statistical analysis of data.

RESULTS

Two hundred and forty two patients with gastrointestinal system malformations were included in the study. Of 242 patients, 135 (55.8%) were male and 107 (44.2%) were female, and their age range was 0-15 years. The most frequent GISM were anorectal malformations (43.2%), atresia involving stomach, ileum or colon (21%) and esophageal atresia/tracheoesophageal fistula (18.3%). Congenital heart defects were observed in 28.5% of the participants. The most frequent defects were as follows; atrial septal defect (31 patients, 44.9%) a, ventricular septal defect (17 patients, 24.6%) and patent ductus arteriosus (5 patients, 7.2%). There was no significant difference (p>0.05) in mortality rate in patients with CHD (16.7%) and without CHD (13.3%) undergoing operations for GISM.

CONCLUSION

We would like to emphasize the importance of the earliest possible cardiological evaluation of all patients with gastrointestinal system malformations.

摘要

目的

确定患有胃肠道畸形(GISM)儿童的先天性心脏缺陷(CHD)发生率以及GISM患者的死亡率。

方法

对我院小儿外科门诊连续随访的242例GISM患儿进行小儿心内科心血管异常检查,并通过回顾性查阅患者记录调查CHD发病率。采用卡方检验对数据进行统计学分析。

结果

242例胃肠道系统畸形患者纳入研究。242例患者中,男性135例(55.8%),女性107例(44.2%),年龄范围为0至15岁。最常见的GISM是肛门直肠畸形(43.2%)、涉及胃、回肠或结肠的闭锁(21%)以及食管闭锁/气管食管瘘(18.3%)。28.5%的参与者存在先天性心脏缺陷。最常见的缺陷如下:房间隔缺损(31例,44.9%)、室间隔缺损(17例,24.6%)和动脉导管未闭(5例,7.2%)。接受GISM手术的CHD患者(16.7%)和无CHD患者(13.3%)的死亡率无显著差异(p>0.05)。

结论

我们想强调对所有胃肠道系统畸形患者尽早进行心脏评估的重要性。

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