大鼠交感神经去节后松果体的超微结构变化。定量研究。
Ultrastructural changes in the rat pineal gland after sympathetic denervation. Quantitative study.
作者信息
Calvo J L, Boya J, García-Mauriño J E
机构信息
Department of Histology and General Embryology, Faculty of Medicine, Complutense University, Madrid, Spain.
出版信息
Histol Histopathol. 1990 Apr;5(2):155-60.
Ultrastructural changes in the rat pineal gland were studied quantitatively 7 and 60 days after the sympathetic denervation by bilateral excission or decentralization of superior cervical ganglia. The surface occupied by pineal parenchymal cells decreased in rats of experimental groups with respect to the control group. Furthermore, profile areas of the cytoplasm, nucleus and nucleolus of the pinealocytes were also diminished. Cytoplasmic lipid droplets in the pinealocytes were markedly decreased in number and size in experimental rats. As demonstrated by the Kruskal-Wallis H test, statistically significant differences were found between rats of the control and operated groups. Rats treated by superior cervical ganglionectomy or decentralization showed morphological changes indicating a hypofunctional pineal gland, although differences were found between both groups.
通过双侧切除或去神经支配颈上神经节，在交感神经去神经支配后7天和60天，对大鼠松果体的超微结构变化进行了定量研究。与对照组相比，实验组大鼠松果体实质细胞所占表面积减少。此外，松果体细胞的细胞质、细胞核和核仁的轮廓面积也减小。实验组大鼠松果体细胞中的细胞质脂滴数量和大小均明显减少。经Kruskal-Wallis H检验表明，对照组和手术组大鼠之间存在统计学上的显著差异。接受颈上神经节切除术或去神经支配的大鼠表现出形态学变化，表明松果体功能减退，尽管两组之间存在差异。
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