The Ohio State University College of Medicine, Columbus, Ohio, USA.
Retina. 2011 Mar;31(3):596-601. doi: 10.1097/IAE.0b013e3181ecccf0.
To report on the presentation, treatment, and outcomes of the largest series to date for patients with endogenous methicillin-resistant Staphylococcus aureus endophthalmitis at a single institution and compare the results from previously published reports of this disease entity.
Retrospective, noncomparative, consecutive case series of patients who were treated for endogenous methicillin-resistant S. aureus endophthalmitis from a single tertiary referral institution were reviewed.
Eight eyes of seven consecutive patients, with a mean age of 58.1 years, were diagnosed with culture-proven endogenous methicillin-resistant S. aureus endophthalmitis. Five patients were male, and six patients had a unilateral presentation. Five of eight eyes were treated with initial vitreous tap and injection of antibiotics, and six eyes showed a retinal detachment during the course of treatment. Final visual acuity ranged from 20/40 to no light perception, and 5 of 8 eyes showed improvement in visual acuity from initial presentation. Only one eye became blind and painful and required enucleation.
This series represents the largest single-institution report on endogenous methicillin-resistant S. aureus endophthalmitis and associated outcomes. Although previously reported cases cited poor visual outcomes and high enucleation rates, the authors' current series shows that retinal detachments are common and enucleation rates are low.
报告在单一机构中迄今为止最大系列的内源性耐甲氧西林金黄色葡萄球菌（MRSA）眼内炎患者的表现、治疗和结局，并比较该疾病实体先前发表的报告中的结果。
回顾性、非对照、连续病例系列，对来自一家三级转诊机构的内源性耐甲氧西林金黄色葡萄球菌眼内炎患者进行治疗。
7 名连续患者的 8 只眼被诊断为培养证实的内源性耐甲氧西林金黄色葡萄球菌眼内炎，平均年龄为 58.1 岁。5 名患者为男性，6 名患者为单侧发病。8 只眼中有 5 只最初接受了玻璃体抽吸和抗生素注射治疗，6 只眼中在治疗过程中出现视网膜脱离。最终视力范围从 20/40 到无光感，8 只眼中有 5 只视力从最初表现开始改善。仅有 1 只眼失明且疼痛，需要眼球摘除。
本系列代表了关于内源性耐甲氧西林金黄色葡萄球菌眼内炎及其相关结局的最大单一机构报告。尽管先前报告的病例提到了较差的视力结果和高眼球摘除率，但作者当前的系列表明，视网膜脱离很常见，眼球摘除率较低。
