来自儿科无症状携带者和咽炎患儿的化脓性链球菌emm型及亚型分离株

Streptococcus pyogenes emm types and subtypes of isolates from paediatric asymptomatic carriers and children with pharyngitis.

作者信息

Blandino Giovanna, Puglisi Salvatore, Speciale Annamaria, Musumeci Rosario

机构信息

Department of Microbiological and Gynecological Sciences, Section of Microbiology, University of Catania, Catania, Italy.

出版信息

New Microbiol. 2011 Jan;34(1):101-4. Epub 2011 Jan 15.

PMID:21344154

Abstract

This study determined emm subtypes of Streptococcus pyogenes strains isolated from asymptomatic carriers and children with pharyngitis. All strains were previously investigated for fibronectin-binding genes (prtF1 and prtF2) and antimicrobial susceptibility. The most significant differences between the two groups, which share only 5 of the 14 detected emmsubtypes, concern the presence of the two more common emmsubtypes, 12.0 (50.0% vs. 3.1%, for asymptomatic carriers and children with pharyngitis, respectively) and 1.0 (28.1% vs. 0%, for children with pharyngitis and asymptomatic carriers, respectively).

摘要

本研究确定了从无症状携带者和咽炎患儿中分离出的化脓性链球菌菌株的emm亚型。所有菌株先前都已针对纤连蛋白结合基因（prtF1和prtF2）及抗菌药敏性进行了研究。两组之间最显著的差异（在检测到的14种emm亚型中仅共有5种）在于两种较常见的emm亚型的存在情况，即emm12.0（无症状携带者和咽炎患儿中分别为50.0%和3.1%）和emm1.0（咽炎患儿和无症状携带者中分别为28.1%和0%）。