Swartz S L, Kraus S J, Herrmann K L, Stargel M D, Brown W J, Allen S D
J Infect Dis. 1978 Oct;138(4):445-54. doi: 10.1093/infdis/138.4.445.
The observation of more than four polymorphonuclear cells (PMN) per high-power field (hpf) in gram-stained smears of urethral secretions was found to differentiate patients with urethritis from patients without urethritis. A urethral discharge was present in 78% of patients with nongonococcal urethritis (NGU). Dysuria without demonstrable urethral discharge and with fewer than four PMN/hpf did not appear to fit into the NGU spectrum. NGU is now defined to include men who have negative urethral cultures for Neisseria gonorrhoeae with a urethral discharge and/or more than four PMN/hpf in their urethral smears. The findings of more than four PMN/hpf in the urethral smears of 22%of asymptomatic sexually active men with more than one sexual partner (polygamous controls) suggests that asymptomatic NGU is not uncommon. Chlamydia trachomatis was isolated significantly more frequently from the NGU study group than from the control group (P less than 0.001). This study adds Corynebacterium vaginale (Haemophilus vaginalis), group B streptococci, and yeasts to the list of sexually transmitted microorganisms that are not etiologic determinants of NGU.
尿道分泌物革兰氏染色涂片每高倍视野（hpf）中多形核白细胞（PMN）超过4个的观察结果被发现可区分尿道炎患者与非尿道炎患者。78%的非淋菌性尿道炎（NGU）患者有尿道分泌物。无明显尿道分泌物且每高倍视野PMN少于4个的排尿困难似乎不符合NGU的范畴。NGU现在被定义为包括尿道分泌物培养淋病奈瑟菌阴性且尿道涂片每高倍视野有尿道分泌物和/或超过4个PMN的男性。在22%有多个性伴侣的无症状性活跃男性（多配偶对照）的尿道涂片中，每高倍视野PMN超过4个的结果表明无症状NGU并不罕见。沙眼衣原体在NGU研究组中的分离频率显著高于对照组（P小于0.001）。本研究将阴道棒状杆菌（阴道嗜血杆菌）、B组链球菌和酵母菌添加到非NGU病因学决定因素的性传播微生物列表中。
