Oh Doo Hwan, Chun Yeoun Sook, Kim Jae Chan
Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2011 Feb;25(1):57-9. doi: 10.3341/kjo.2011.25.1.57. Epub 2011 Jan 17.
We report the first case of ocular benign lymphoid hyperplasia (BLH) treated with subconjunctival injection of bevacizumab (Avastin). A 27-year-old man presented to our clinic with conjunctival masses and limbal neovascularization. An incisional biopsy yielded the diagnosis of BLH. The patient was subsequently given a subconjunctival injection of bevacizumab (1.25 mg / 0.1 mL). The patient did not experience recurrence or malignant metaplasia during the one-year follow-up period. In patients with conjunctival BLH, subconjunctival injection of bevacizumab can be a useful treatment option in patients unable to undergo a surgical procedure due to limbal neovascularization.
我们报告了首例采用贝伐单抗(阿瓦斯汀)结膜下注射治疗的眼部良性淋巴组织增生症(BLH)。一名27岁男性因结膜肿物和角膜缘新生血管来到我们诊所。切开活检确诊为BLH。随后该患者接受了贝伐单抗结膜下注射(1.25毫克/0.1毫升)。在一年的随访期内,患者未出现复发或恶性化生。对于患有结膜BLH且因角膜缘新生血管而无法接受手术的患者,结膜下注射贝伐单抗可能是一种有效的治疗选择。