Verin P, Gendre P, Andrianjafy H, Mortemousque B
Centre des Spécialités, Service OPH, Bordeaux.
Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1990;67:175-9.
Electron-microscopic examination of conjunctival and corneal biopsies from six apparently healed trachomatous patients demonstrated chlamydiae in situ. Nine previously trachomatous patients were submitted to the same biopsies; all biopsies were positives. After two months specific anti-chlamydial treatment, we observed the same result before anterior segment surgery. Nevertheless surgery was performed without consequences except for the two corneal grafts which failed. We must ask for two questions: how long chlamydial particles persist in trachomatous tissue? What is the real efficacy of topical anti-chlamydial drugs?
对6名明显已治愈的沙眼患者的结膜和角膜活检样本进行电子显微镜检查，发现衣原体原位存在。9名曾患沙眼的患者接受了同样的活检；所有活检结果均为阳性。在进行了两个月的特异性抗衣原体治疗后，我们在眼前段手术前观察到了相同的结果。然而，除了两片角膜移植失败外，手术进行得没有出现其他问题。我们必须提出两个问题：沙眼组织中的衣原体颗粒会持续存在多长时间？局部抗衣原体药物的实际疗效如何？
