Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Pediatr Nephrol. 2011 May;26(5):789-93. doi: 10.1007/s00467-011-1792-2. Epub 2011 Feb 25.
Little information is available on adherence to a home automated peritoneal dialysis (APD) prescription for children with end-stage renal disease. We have therefore retrospectively reviewed HomeChoice PRO Card data from patients <21 years of age who received home APD. Adherence was characterized as occurring ≥ 95%, 90-94%, or <90% of time by dividing the frequency of each of four measured prescription variables (sessions/month, duration of each session, number of cycles/session, volume of dialysate/session) by the prescribed frequency and multiplying by 100. The relationship between treatment adherence and patient age, gender, race and if the patient had received training, respectively, was assessed. Of the 51 patients (57% male), with a mean age at peritoneal dialysis (PD) onset of 11.8 ± 5.3 years, 28 (55%) were adherent for all variables. No difference in mean age or if patients were trained existed between the two groups. Males were more likely to be non-adherent (p = 0.026) as were African Americans (p = 0.048). The majority of patients were adherent to duration (96%) and number of cycles (92%), whereas non-adherence was more common with number of sessions (82%) and dialysate volume (78%). In conclusion, 45% of the pediatric patients in our study cohort exhibited some non-adherence to their prescribed APD regimen, emphasizing the value of closely monitoring the performance of home dialysis in children.
关于终末期肾病儿童遵循家庭自动化腹膜透析（APD）处方的信息很少。因此，我们回顾性地审查了接受家庭 APD 治疗的 <21 岁患者的 HomeChoice PRO 卡数据。通过将四个测量处方变量（每月次数、每次持续时间、每次循环次数、每次透析液量）的每个变量的频率除以规定频率并乘以 100，将依从性定义为发生≥95%、90-94%或<90%的时间。评估了治疗依从性与患者年龄、性别、种族以及患者是否接受过培训之间的关系。在 51 名患者（57%为男性）中，腹膜透析（PD）起始时的平均年龄为 11.8 ± 5.3 岁，28 名（55%）患者在所有变量上均依从。两组之间的平均年龄或患者是否接受培训没有差异。男性更有可能不依从（p = 0.026），非裔美国人也更有可能不依从（p = 0.048）。大多数患者对持续时间（96%）和循环次数（92%）的依从性较高，而对治疗次数（82%）和透析液量（78%）的依从性较低。总之，我们研究队列中的 45%儿科患者对其规定的 APD 方案存在一定程度的不依从，这强调了密切监测儿童家庭透析表现的重要性。
