Department of Dermatology, Shimane University Faculty of Medicine, Izumo, Japan.
J Dermatol. 2010 May;37(5):493-5. doi: 10.1111/j.1346-8138.2010.00865.x.
We describe a case of granuloma annulare (GA) associated with Sjögren's syndrome (SS) in a 69-year-old woman. She complained of erythematous plaques on the left forearm and neck in addition to dry eyes and mouth. The laboratory and clinical findings also fulfilled the criteria for diagnosis of SS. Histopathological examination revealed the features of interstitial type GA. It is not rare that granulomatous diseases are associated with autoimmune diseases. This case indicated that granulomatous diseases and SS are closely related and that GA should be recognized as a cutaneous manifestation associated with autoimmune diseases, including SS.
我们描述了一例 69 岁女性伴发干燥综合征(SS)的环状肉芽肿(GA)。患者主诉左前臂和颈部出现红斑斑块,同时伴有眼干和口干。实验室和临床检查也符合 SS 的诊断标准。组织病理学检查显示间质性 GA 的特征。肉芽肿性疾病与自身免疫性疾病相关并不罕见。本病例提示,肉芽肿性疾病与 SS 密切相关,GA 应被视为与包括 SS 在内的自身免疫性疾病相关的皮肤表现。