Schmelzeisen R, Buchweitz I K, Fricke A, Frölich J
Klinik und Poliklinik für Mund-, und Gesichtschirurgie, Medizinische Hochschule Hannover.
Dtsch Z Mund Kiefer Gesichtschir. 1990 Nov-Dec;14(6):442-6.
In a placebo-controlled double-blind study using 3 x 400 mg ibuprofen during the surgical removal of impacted and dislocated third molars, a pain reduction of 64% (p = 0.05) as against the placebo control group could be demonstrated on the day of surgery and the first postoperative day. In view of the published results of a double-blind study on the reduction of cheek swelling using dexamethasone, the perioperative combination of 3 x 600 mg ibuprofen with 2 x 6 mg dexamethasone seems to be helpful in reliably preventing pain and swelling after dental surgery.
在一项安慰剂对照双盲研究中，在外科手术拔除阻生和脱位的第三磨牙期间使用3×400毫克布洛芬，在手术当天和术后第一天，与安慰剂对照组相比，疼痛减轻了64%（p = 0.05）。鉴于已发表的关于使用地塞米松减轻脸颊肿胀的双盲研究结果，3×600毫克布洛芬与2×6毫克地塞米松的围手术期联合使用似乎有助于可靠地预防牙科手术后的疼痛和肿胀。
