Department of Gastroenterological Surgery, Toho University Medical Center, Omori Hospital, 6-11-1 Omori nishi, Tokyo, 143-8541, Japan.
World J Surg Oncol. 2011 Feb 28;9:28. doi: 10.1186/1477-7819-9-28.
Metastasis to the abdominal wall including port sites after laparoscopic surgery for colorectal cancer is rare. Resection of metastatic lesions may lead to greater survival benefit if the abdominal wall metastasis is the only manifestation of recurrent disease. A 57-year-old man, who underwent laparoscopic surgery for advanced mucinous adenocarcinoma of the cecum 6 years prior, developed a nodule in the surgical wound at the lower right abdomen. Although tumor markers were within normal limits, the metastasis to the abdominal wall and abdominal cavity from the previous cecal cancer was suspected. An abdominal computed tomography scan did not provide detective evidence of metastasis. (18)F-fluorodeoxyglucose positron emission/computed tomography ((18)F-FDG PET/CT) was therefore performed, which demonstrated increased (18)F-fluorodeoxyglucose uptake (maximum standardized uptake value: 3.1) in the small abdominal wall nodule alone. Histopathological examination of the resected nodule confirmed the diagnosis of metastatic mucinous adenocarcinoma. Prognosis of intestinal mucinous adenocarcinoma is reported to be poorer than that of non-mucinous adenocarcinoma. In conclusion, this case suggests an important role of (18)F-FDG PET/CT in early diagnosis and decision-making regarding therapy for recurrent disease in cases where a firm diagnosis of recurrent colorectal cancer is difficult to make.
腹壁转移包括结直肠癌腹腔镜手术后的端口部位转移较为罕见。如果腹壁转移是复发性疾病的唯一表现,切除转移病灶可能会带来更大的生存获益。一位 57 岁男性,6 年前因盲肠高级黏液性腺癌接受了腹腔镜手术,在右下腹部的手术伤口处出现了一个结节。尽管肿瘤标志物在正常范围内,但仍怀疑是先前盲肠癌转移至腹壁和腹腔。腹部 CT 扫描未提供转移的探测证据。因此进行了氟代脱氧葡萄糖正电子发射/计算机断层扫描(18F-FDG PET/CT),结果显示小腹部结节单独摄取增加(18F-FDG 最大标准化摄取值:3.1)。切除结节的组织病理学检查证实了转移性黏液性腺癌的诊断。肠黏液性腺癌的预后比非黏液性腺癌差。总之,本例提示在难以明确诊断复发性结直肠癌的情况下,18F-FDG PET/CT 在早期诊断和治疗复发性疾病方面具有重要作用。